Well absorbed. Relationship to plasma proteins – 40%. It is metabolized in the liver to inactive metabolites glyukuronizirovannyh. It is shown mainly in the kidney as metabolites or unchanged.
Pain severe halotestin for sale and moderate severity of various origins (malignancy, trauma, acute pancreatitis, peptic ulcer and 12 duodenal ulcer, biliary colic, renal colic, intestinal colic, pre- and postoperative periods, Leriche syndrome, occlusive disease), painful diagnostic procedure.
Hypersensitivity to any component of the drug, inhibition of the respiratory center, respiratory insufficiency, liver and / or kidney failure, coma, alcohol intoxication, acute intoxication of hypnotic drugs, analgesics, opioids or other psychotropic drugs, hypotension, organic diseases of the central nervous system, epilepsy, or tonic-clonic seizures in the history of bronchial asthma, pregnancy, lactation, children under 18 years.
older age, myxedema, hypothyroidism, adrenal insufficiency, depression of the central nervous system, brain injury with psychosis, prostatic hyperplasia, stricture of the urethra, halotestin for sale alcoholism, abuse of drugs or drug dependence, emotional lability, suicidal thoughts or attempts ( including history), general grave condition of patients with opioid dependence. In patients with established severe opioid intolerance allergic and nonallergic origin; with a tendency to abuse drugs or drug addiction treatment should be carried out Prosidolom short courses and under medical supervision.
Dosing and Administration
The tablet lay between the upper lip and gum or under the tongue and hold until resorption. The dosage and frequency of administration of the drug are established physician in view of the intensity of pain and the patient’s condition. Indicative dosing regimen – 10-20 mg 2-3 times a day. The maximum daily dose-250 mg.
From the nervous system:
dizziness, muscle weakness, headache, seizures, narcolepsy. From the digestive system:
dry mouth, nausea, vomiting, abnormal liver function, intestinal atony.
decrease in blood pressure, bradycardia.
From the urogenital system:
atony bladder, renal dysfunction, amenorrhea, decreased libido.
Other: addiction, “cancellation” syndrome.
Symptoms: respiratory depression, increased, the severity of side effects, cramps, vomiting, collapse, disorder; consciousness up to coma, convulsions, depression of the respiratory center up to respiratory paralysis.
Treatment: washing stomach naloxone at a dose of 0.4 – 2 mg (in the absence of the effect of naloxone can be repeated after 2-3 min), obspechenie adequate pulmonary ventilation and symptomatic therapy.Possible treatment of overdose of narcotic analgesics.
Interaction with other drugs
Do dampening effect on the central nervous system of other narcotic analgesics, sedatives and hypnotic drugs, antipsychotics, anxiolytics, drugs for general anesthesia, ethanol, and monoamine oxidase inhibitors.
Enhances the effect of halotestin for sale antihypertensive drugs.
Naloxone and naltrexone are specific antagonists Prosidola.
In the period of treatment should refrain from driving motor vehicles and activities potentially hazardous activities that require high concentration and psychomotor speed reactions. Not allowed the use of ethanol. Perhaps the development of addiction, and the syndrome of “cancellation”. In patients with a tendency to abuse drugs or drug addiction treatment should be carried out Prosidolom short courses and under medical supervision.
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